Marine Drugs | |
The Lipid A from the Haloalkaliphilic Bacterium |
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Sara Carillo3  Giuseppina Pieretti3  Buko Lindner1  Ida Romano2  Barbara Nicolaus2  Rosa Lanzetta3  Michelangelo Parrilli3  | |
[1] Division of Immunochemistry, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Parkallee 10, D-23845 Borstel, Germany; E-Mail:;CNR Institute of Biomolecular Chemistry (ICB-CNR), National Research Council (CNR), Via Campi Flegrei 34, 80078 Pozzuoli, Italy; E-Mails:;Department of Chemical Sciences, University of Naples “Federico II”, Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Naples, Italy; E-Mails: | |
关键词:
endotoxin;
lipid A;
mass spectrometry;
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DOI : 10.3390/md11010184 | |
来源: mdpi | |
【 摘 要 】
Lipid A is a major constituent of the lipopolysaccharides (or endotoxins), which are complex amphiphilic macromolecules anchored in the outer membrane of Gram-negative bacteria. The glycolipid lipid A is known to possess the minimal chemical structure for LPSs endotoxic activity, able to cause septic shock. Lipid A isolated from extremophiles is interesting, since very few cases of pathogenic bacteria have been found among these microorganisms. In some cases their lipid A has shown to have an antagonist activity,
【 授权许可】
CC BY
© 2013 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190039139ZK.pdf | 604KB | download |