期刊论文详细信息
Nutrients
Does Milk Cause Constipation? A Crossover Dietary Trial
Elesa T. Crowley1  Lauren T. Williams2  Tim K. Roberts3  Richard H. Dunstan3 
[1] Department of Rural Health NSW, University of Newcastle, Tamworth, NSW 2340, Australia;Nutrition and Dietetics, University of Canberra, Bruce, ACT 2617, Australia; E-Mail:;School of Environmental and Life Sciences, University of Newcastle, Callaghan, NSW 2308, Australia; E-Mails:
关键词: constipation;    child;    hypersensitivity;    soy;    casein;   
DOI  :  10.3390/nu5010253
来源: mdpi
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【 摘 要 】

The aims of this study were to: (1) determine whether replacement of cow’s milk protein with soy resolves Chronic Functional Constipation (CFC); and (2) investigate the effects of cow’s milk β casein A1 and cow’s milk β casein A2 on CFC. Children diagnosed with CFC were recruited to one of two crossover trials: Trial 1 compared the effects of cow’s milk and soy milk; Trial 2 compared the effects of cow’s milk β casein A1 and cow’s milk β casein A2. Resolution of constipation was defined as greater than eight bowel motions during a two week intervention. Thirteen children (18 to 144 months) participated in Trial 1 (6 boys, 7 girls). Nine participants who completed the soy epoch all experienced resolution (p < 0.05). Thirty-nine children (21 to 144 months) participated in Trial 2 (25 boys, 14 girls). Resolution of constipation was highest during the washout epoch, 81%; followed by cow’s milk β casein A2, 79%; and cow’s milk β casein A1, 57%; however, the proportions did not differ statistically. The results of Trial 1 demonstrate an association between CFC and cow’s milk consumption but Trial 2 failed to show an effect from type of casein. Some other component in cow’s milk common to both A1 and A2 milk may be causing a problem in these susceptible children.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.

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