Steroid Nanocrystals Prepared Using the Nano Spray Dryer B-90

Pharmaceutics

Koichi Baba¹ 

关键词: steroid;    fluorometholone;    dexamethasone;    drug nanocrystals;    Nano Spray Dryer B-90;   

DOI  :  10.3390/pharmaceutics5010107

来源: mdpi

【 摘 要 】

The Nano Spray Dryer B-90 offers a new, simple, and alternative approach for the production of drug nanocrystals. In this study, the preparation of steroid nanocrystals using the Nano Spray Dryer B-90 was demonstrated. The particle size was controlled by selecting the mesh aperture size. Submicrometer steroid particles in powder form were successfully obtained. These nanoparticles were confirmed to have a crystal structure using powder X-ray diffraction pattern analysis. Since drug nanocrystals have recently been considered as a novel type of drug formulation for drug delivery systems, this study will be useful for nano-medical applications.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.