Microwave-Enhanced Cross-Coupling Reactions Involving Alkynyltrifluoroborates with Aryl Bromides

Molecules

Vitali Coltuclu¹  Eric Dadush¹  Abhijit Naravane¹ 

[1] Departments of Chemistry and Radiology, University of Tennessee, Knoxville, TN 37996, USA

关键词: organotrifluoroborates;    alkynes;    microwave;    coupling reactions;   

DOI  :  10.3390/molecules18021755

来源: mdpi

【 摘 要 】

Palladium-catalyzed alkynylation has emerged as one of the most reliable methods for the synthesis of alkynes which are often used in natural product syntheses and material science. An efficient method for coupling alkynyltrifluoroborates with various aryl bromides in the presence of a palladium catalyst has been developed using microwave irradiation. The microwave reactions are rapid and efficient.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.