An Efficient Microwave-Assisted Suzuki Reaction using a New Pyridine-Pyrazole/Pd(II) Species as Catalyst in Aqueous Media

Molecules

Liqun Shen¹  Suyu Huang¹  Yuanmei Nie¹ 

[1] Key Laboratory of Development and Application of Forest Chemicals of Guangxi, College of Chemistry and Chemical Engineering, Guangxi University for Nationalities, Nanning, 530006, China

关键词: Suzuki coupling;    pyridine-pyrazole;    palladium;    aqueous media;   

DOI  :  10.3390/molecules18021602

来源: mdpi

【 摘 要 】

A new pyridine-pyrazole N–N ligand has been conveniently synthesized and characterized by ¹H-, ¹³C-NMR, IR spectroscopies, HRMS and X-ray single-crystal crystallography analyses. The ligand adds to palladium(II) under basic conditions to give high yields of an air-stable and water-soluble complex that was fully characterized by NMR and HRMS. The complex was investigated as a catalyst for the Suzuki reaction in aqueous media under microwave irradiation. The compound proved to be an effective catalyst.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.