A Review of Aspects of Oxidative Hair Dye Chemistry with Special Reference to N-Nitrosamine Formation

Materials

David Lewis¹  John Mama¹ 

[1] Perachem Limited, 1 Sizers Court, Henshaw Lane, Yeadon, Leeds LS19 7DP, UK;

关键词: hair dye;    N-nitroso compounds (NOC);    nitrosamine;    p-phenylenediamine (PPD);    cancer;    risk;   

DOI  :  10.3390/ma6020517

来源: mdpi

【 摘 要 】

This review discusses a new aspect to the safety profile of oxidative hair dyes using data already in the public domain. These dyes contain secondary amines that are capable of forming potentially carcinogenic nitrosamine derivatives when exposed to atmospheric pollution. Numerous scientific articles confirm the existence of secondary amines in hair dyes (and their intermediates), the possibility of nitrosation by atmospheric NO_x of secondary amines to give the N-nitrosamines, and the significant safety risks on N-nitrosamines. It is believed that such nitrosamine derivatives should be investigated more fully in the interests of consumer safety.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.