A New Hydroxychavicol Dimer from the Roots of Piper betle

Molecules

Chwan-Fwu Lin³  Tsong-Long Hwang²  Chun-Chien Chien¹  Huei-Yu Tu⁴ 

[1] Department of Dentistry, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan; E-Mail:;Cell Pharmacology Laboratory, Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan; E-Mail:;Department of Cosmetic Science, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan; E-Mail:;Department of Plant Industry, National Pingtung University of Science and Technolog, Pingtung 912, Taiwan; E-Mail:

关键词: Piper betle;    2-(γ'-hydroxychavicol)-hydroxychavicol;    hydroxychavciol;    superoxide anion;    elastase;    neutrophils;   

DOI  :  10.3390/molecules18032563

来源: mdpi

【 摘 要 】

A new hydroxychavicol dimer, 2-(γ'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.