Insecticidal and Feeding Deterrent Effects of Fraxinellone from Dictamnus dasycarpus against Four Major Pests

Molecules

Min Lü¹  Wenjun Wu² 

[1] Institute of Pesticide Science, College of Plant Protection, Northwest A&F University, Yangling 712100, Shaanxi, China; E-Mail

关键词: fraxinellone;    antifeedant activity;    ovicidal action;    development change;   

DOI  :  10.3390/molecules18032754

来源: mdpi

【 摘 要 】

Fraxinellone, a well-known and significant naturally occurring compound isolated from Meliaceae and Rutaceae spp. has been widely used as a drug for the treatment of tumors. On the other hand, fraxinellone exhibited a variety of insecticidal activities including feeding-deterrent activity, inhibition of growth, and larvicidal activity. The present study focused on the antifeedant and larvicidal activities of fraxinellone against the larvae of Lepidoptera, including Mythimna separata, Agrotis ypsilon, Plutella xylostella, and one kind of sanitary pest, Culux pipiens pallens. Meanwhile, the ovicidal activities and the effects of fraxinellone on the larval development of M. separata were also observed. The LC₅₀ values of fraxinellone against 3rd instar larvae of M. separata, 2nd instar larvae of P. xylostella and 4th instar larvae of C. pipiens pallens were 15.95/6.43/3.60 × 10⁻² mg mL⁻¹, and its AFC₅₀ values against 5th instar larvae of M. separata, 2nd instar larvae of P. xylostella and 2nd instar larvae of A. ypsilon were 10.73/7.93/12.58 mg mL⁻¹, respectively. Compared with the control group, fraxinellone obviously inhibited the pupation rate and the growth of M. separata. Once M. separata was treated with fraxinellone at concentrations of 5.0, 10.0, and 20.0 mg mL⁻¹, respectively, the stages from the larvae to adulthood and the egg hatching duration were prolonged to 1/2/3, and 4/3/4 days, respectively. Additionally, fraxinellone strongly inhibited the development rate and the egg hatch proportion of M. separata.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.