期刊论文详细信息
Journal of Clinical Medicine
The Treatment of Verrucae Pedis Using Falknor’s Needling Method: A Review of 46 Cases
Belinda Longhurst1 
[1] Winchester Podiatry, Winchester, SO23 9QX, UK; E-Mail:
关键词: wart;    verrucae;    HPV;    foot;    plantar;    virus;    infection;   
DOI  :  10.3390/jcm2020013
来源: mdpi
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【 摘 要 】

Human Papilloma Virus (HPV) related verrucae pedis persist, seemingly evading host immune surveillance, yet sometimes disappear with inflammation. The absence, or reduction, of a cellular immune response may explain why verrucae treatments are not uniformly successful and treatment can be difficult even in immune-competent individuals. Little investigation has been undertaken into the potential benefit and efficacy of needling verrucae, a treatment modality causing HPV infected keratinocyte destruction in addition to inducing an assumed enhanced immune response. A review of clinical practice is presented, reporting the treatment method and results of data collected from a retrospective review of 45 patients. Thirty-one (69%) cases demonstrated complete resolution of verrucae following needling treatment. Three patients demonstrated reduction in size and pain whilst 11 showed no improvement. No adverse events were noted. Needling may have a place in the management of verrucae pedis in an adult population but a large scale study utilising objective measures and a control intervention would provide more detailed efficacy data along with a greater understanding of the effects of this treatment on long term immunity.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.

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