Molecules | |
Synthesis, Structure and Cytotoxic Activity of New Acetylenic Derivatives of Betulin | |
Stanisᐪw Boryczka2  Ewa B𑦾nek2  Joanna Wietrzyk3  Katarzyna Kempińska3  Maria Jastrzᆛska1  Joachim Kusz4  | |
[1] Department of Solid State Physics, Institute of Physics, University of Silesia, 4 Uniwersytecka Str., 40-007 Katowice, Poland;Department of Organic Chemistry, Medical University of Silesia, 4 Jagiellonska Str., 41-200 Sosnowiec, Poland;Department of Experimental Oncology, Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 R. Weigla Str., 53-114 Wrocław, Poland;Department of Physics of Crystals, Institute of Physics, University of Silesia, 4 Uniwersytecka Str., 40-007 Katowice, Poland | |
关键词: acetylenic betulins; synthesis; crystal structure; cytotoxic activity; | |
DOI : 10.3390/molecules18044526 | |
来源: mdpi | |
【 摘 要 】
A new series of betulin derivatives containing one or two pharmacophores bearing an acetylenic and carbonyl function at the C-3 and/or C-28 positions has been synthesized and characterized by 1H- and 13C-NMR, IR, MS and elemental analyses. The crystal structure of 28-
【 授权许可】
CC BY
© 2013 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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