2-{[5-(Diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide

Molbank

Prakash S. Nayak¹  Badiadka Narayana¹  Seranthimata Samshuddin¹ 

[1] ¹Department of Studies in Chemistry, Mangalore University, Mangalagangotri-574 199, Karnataka, India ²Research Department of Chemistry, P. A. College of Engineering, Nadupadavu, Mangalore 574153, Karnataka, India

关键词: 1;    3;    4-oxadiazole;    pyrazine;    S-alkylation;    thioether;   

DOI  :  10.3390/M800

来源: mdpi

【 摘 要 】

S-Alkylation of 5-(diphenylmethyl)-1,3,4-oxadiazole-2(3H)-thione (3) by 2-chloro-N-(pyrazin-2-yl)acetamide (2) affords the title compound, 2-{[5-(diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide (4). The intermediate (2), in turn, was prepared by the acetylation of 2-aminopyrazine (1) with chloroacetyl chloride. The structure of the newly synthesized compound is characterized by IR, NMR and mass spectral data.

【 授权许可】

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