International Journal of Molecular Sciences | |
Danger Control Programs Cause Tissue Injury and Remodeling | |
Jan H. Hagemann1  Holger Haegele1  Susanna Müller2  | |
[1] Nephrologisches Zentrum, Medizinische Klinik und Poliklinik IV der Ludwig-Maximilians Universität, München 80336, Germany; E-Mails:;Pathologisches Institut, Ludwig-Maximilians Universität, München 80336, Germany; E-Mail: | |
关键词: regeneration; fibrosis; coagulation; stem cells; inflammation; acute kidney injury; chronic kidney disease; healing; repair; | |
DOI : 10.3390/ijms140611319 | |
来源: mdpi | |
【 摘 要 】
Are there common pathways underlying the broad spectrum of tissue pathologies that develop upon injuries and from subsequent tissue remodeling? Here, we explain the pathophysiological impact of a set of evolutionary conserved danger control programs for tissue pathology. These programs date back to the survival benefits of the first multicellular organisms upon traumatic injuries by launching a series of danger control responses,
【 授权许可】
CC BY
© 2013 by the authors; licensee MDPI, Basel, Switzerland
【 预 览 】
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RO202003190036157ZK.pdf | 8227KB | download |