The Effect of 3-Thiopheneacetic Acid in the Polymerization of a Conductive Electrotextile for Use in Biosensor Development

Biosensors

Shannon K. McGraw²  Evangelyn Alocilja²  Andre Senecal¹ 

[1] Food Protection Team, U.S. Army Natick Soldier Research, Development, and Engineering Center (NSRDEC), Natick, MA 01760, USA; E-Mail:;Biosystems and Agricultural Engineering, Michigan State University, 524 S. Shaw Lane, 115 Farrall Hall, East Lansing, MI 48824, USA; E-Mail:

关键词: 3-thiopheneacetic acid;    electrotextile;    biosensor;    polypyrrole;    antibody attachment;   

DOI  :  10.3390/bios3030286

来源: mdpi

【 摘 要 】

Investigations were conducted to develop an electrotextile using a nonwoven polypropylene fiber platform conformally coated in a conductive, functionalized copolymer of polypyrrole and 3-thiopheneacetic acid (3TAA). The objectives of this study were to determine: (1) if the inclusion of 3TAA in the polymerization process would have an effect on the availability of binding sites in the high-surface area electrotextile for biorecognition elements and (2) how the increase in the concentration of 3TAA would affect the physical characteristics of the coating, resistivity of the sample and availability of binding sites. It was found that the addition of 3TAA to the polymerization process resulted in an increase in the size of the polypyrrole coating, as well as the material resistivity and available binding sites for biorecognition elements. These factors were used to determine which of the tested concentrations was best for biosensor development. A polymer coated membrane sample containing a concentration within the range of 10–50 mg/mL of 3TAA was selected as the best for future biosensor work.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.