Early Lung Cancer Diagnosis by Biosensors

International Journal of Molecular Sciences

Yuqian Zhang¹  Dongliang Yang¹  Lixing Weng² 

[1] Key Laboratory for Organic Electronics & Information Displays (KLOEID) and Institute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications, 9 Wenyuan Road, Nanjing 210023, China; E-Mails:;College of Geography and Biological Information, Nanjing University of Posts and Telecommunications, 9 Wenyuan Road, Nanjing 210023, China

关键词: lung cancer;    early diagnosis;    biomarker;    microRNA;    tumor-associated antigen;    biosensor;   

DOI  :  10.3390/ijms140815479

来源: mdpi

【 摘 要 】

Lung cancer causes an extreme threat to human health, and the mortality rate due to lung cancer has not decreased during the last decade. Prognosis or early diagnosis could help reduce the mortality rate. If microRNA and tumor-associated antigens (TAAs), as well as the corresponding autoantibodies, can be detected prior to clinical diagnosis, such high sensitivity of biosensors makes the early diagnosis and prognosis of cancer realizable. This review provides an overview of tumor-associated biomarker identifying methods and the biosensor technology available today. Laboratorial researches utilizing biosensors for early lung cancer diagnosis will be highlighted.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland