Chemical Composition and Biological Activities of Essential Oils of Eremanthus erythropappus (DC) McLeisch (Asteraceae)

Molecules

Marcelo S. Silvério¹  Glauciemar Del-Vechio-Vieira¹  Míriam A. O. Pinto¹  Maria S. Alves¹ 

[1] Department of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Juiz de Fora, São Pedro, Juiz de Fora, Minas Gerais 36036-330, Brazil;

关键词: Eremanthus erythropappus;    essential oil;    β-caryophyllene;    germacrene-D;    α-bisabolol;    antimicrobial activity;    antioxidant activity;   

DOI  :  10.3390/molecules18089785

来源: mdpi

【 摘 要 】

The chemical composition of the essential oils obtained by hydrodistillation of different parts of Eremanthus erythropappus, including leaves, branches and inflorescences, was investigated by Gas Chromatography and Gas Chromatography/Mass Spectrometry. The antimicrobial activity of the oils was assessed by the disc diffusion and microdilution methods, while the antioxidant activity was evaluated by DPPH and reducing power tests. The main compounds found in the essential oils derived from the inflorescences and leaves were β-caryophyllene, germacrene-D, α-copaene and β-pinene. α-Bisabolol was the major component in the branches. The oils were active against Staphylococcus aureus, Streptococcus pyogenes and fungi, but not Escherichia coli and Pseudomonas aeruginosa. The MIC values ranged from 0.01 to 0.50 mg/mL. Using the DPPH test, the IC₅₀ values ranged from 38.77 ± 0.76 to 102.24 ± 1.96 μg/mL, while the reducing power test produced IC₅₀ values between 109.85 ± 1.68 and 169.53 ± 0.64 μg/mL. The results revealed that the E. erythropappus oils are new promising potential sources of antimicrobial and antioxidant compounds with good future practical applications for human health.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.