Three Novel Xanthones from Garcinia paucinervis and Their Anti-TMV Activity

Molecules

Yu-Ping Wu²  Wei Zhao¹  Zhen-Yuan Xia²  Guang-Hui Kong²  Xiu-Ping Lu²  Qiu-Fen Hu² 

[1] Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, China; E-Mail:;Yunnan Academy of Tobacco Agricultural Sciences, Yuxi 653100, China; E-Mails:

关键词: Garcinia paucinervis;    xanthones;    anti-tobacco mosaic virus;   

DOI  :  10.3390/molecules18089663

来源: mdpi

【 摘 要 】

Phytochemical investigations of the leaves of Garcinia paucinervis resulted in the isolation of three new xanthones 1–3 and five known analogues 4–8. Structural elucidations of 1–3 were performed by spectral methods such as 1D and 2D (HMQC, HMBC, and ROESY) NMR spectroscopy, in addition to high resolution mass spectrometry. Compounds 1–3 showed anti-TMV activities, with inhibition rates above 20%, especially for 1, which had a lower IC₅₀ value of 21.4 µM.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.