期刊论文详细信息
International Journal of Molecular Sciences | |
Molecular Interactions in the Development of Brain Metastases | |
Nina Martinez1  Adrienne Boire1  | |
关键词: CNS metastasis; metastatic cascade; vascular co-option; dormancy; | |
DOI : 10.3390/ijms140817157 | |
来源: mdpi | |
【 摘 要 】
Brain metastases are a much-feared complication of cancer. The development of brain metastases requires a malignant cell to acquire characteristics that facilitate dissemination away from the primary site, entrance into the nervous system, and establishment in the brain. This review summarizes recent work focused on the molecular derangements leading to brain metastases and outlines areas in need of greater understanding.
【 授权许可】
CC BY
© 2013 by the authors; licensee MDPI, Basel, Switzerland
【 预 览 】
Files | Size | Format | View |
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RO202003190033870ZK.pdf | 176KB | download |