Open Access Integrated Therapeutic and Diagnostic Platforms for Personalized Cardiovascular Medicine

Journal of Personalized Medicine

Patrick A. Gladding⁴  Andrew Cave⁸  Mehran Zareian⁴  Kevin Smith⁴  Jagir Hussan⁶  Peter Hunter⁶  Folarin Erogbogbo³  Zoraida Aguilar¹⁰  David S. Martin⁷  Eugene Chan⁵  Margie L. Homer⁹  Abhijit V. Shevade⁹  Mohammad Kassemi¹  James D. Thomas^2,4 

[1] NASA Glenn Research Center, 21000 Brookpark Rd, Cleveland, OH 44135, USA; E-Mail:;National Space Biomedical Research Institute, 6500 Main Street, Suite 910, Houston, TX 77030-1402, USA; E-Mail:;Institute for Lasers, Photonics and Biophotonics, 428 Natural Science Complex, University at Buffalo, NY 14260-3000, USA; E-Mail:;Theranostics Laboratory Ltd, North Shore Hospital, Private Bag 93503, Auckland 0622, New Zealand; E-Mails:;DNA Medicine Institute, 727 Massachusetts Avenue, Cambridge, MA 02139, USA; E-Mail:;Auckland Bioengineering Institute, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand ; E-Mails:;Wyle Science, Technology and Engineering Group, 1200 Hercules, Houston, TX 77058, USA; E-Mail:;Waitemata District Health Board, North Shore Hospital, Private Bag 93503, Auckland 0622, New Zealand; E-Mail:;Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Dr, Pasadena, CA 91109, USA; E-Mails:;Ocean NanoTech, 2143 Worth Lane, Springdale, AR 72764, USA; E-Mail:

关键词: pharmacogenomics;    echocardiography;    electrocardiography;    personalized medicine;    genomics;   

DOI  :  10.3390/jpm3030203

来源: mdpi

【 摘 要 】

It is undeniable that the increasing costs in healthcare are a concern. Although technological advancements have been made in healthcare systems, the return on investment made by governments and payers has been poor. The current model of care is unsustainable and is due for an upgrade. In developed nations, a law of diminishing returns has been noted in population health standards, whilst in the developing world, westernized chronic illnesses, such as diabetes and cardiovascular disease have become emerging problems. The reasons for these trends are complex, multifactorial and not easily reversed. Personalized medicine has the potential to have a significant impact on these issues, but for it to be truly successful, interdisciplinary mass collaboration is required. We propose here a vision for open-access advanced analytics for personalized cardiac diagnostics using imaging, electrocardiography and genomics.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.