Understanding the Nucleophilic Character and Stability of the Carbanions and Alkoxides of 1-(9-Anthryl)ethanol and Derivatives

Molecules

Ramsés E. Ramírez²  Cirilo Garc໚-Martínez¹ 

[1] Área de Química, Departamento de Ciencias Básicas, Universidad Autónoma Metropolitana-Azcapotzalco, San Pablo #180, Col. Reynosa, Mexico, D. F., 02200 México; E-Mail:;Departamento de Fisicomatemáticas, Facultad de Ciencias Químicas, Av. San Claudio y 14 Sur, Col. San Manuel, Benemérita Universidad Autónoma de Puebla, C.P. 72570, Puebla, Pue., Mexico; E-Mail:

关键词: absolute gas phase acidity;    alkoxide;    carbanion;    Fukui function;    nucleophile;   

DOI  :  10.3390/molecules180910254

来源: mdpi

【 摘 要 】

The nucleophilic character and stability of the carbanions vs. alkoxides derived from 2,2,2-trifluoro-1-(9-anthryl)ethanol and 1-(9-anthryl)ethanol containing X electron-releasing and X electron-acceptor substituents attached to C-10, have been studied at the B3LYP/6-31+G(d,p) level of theory. Results analyzed in terms of the absolute gas-phase acidity, Fukui function, the local hard and soft acids and bases principle, and the molecular electrostatic potential, show that the central ring of the 9-anthryl group confers an ambident nucleophilic character and stabilizes the conjugated carbanion by electron-acceptor delocalization.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.