International Journal of Environmental Research and Public Health | |
Pulmonary Oxidative Stress, Inflammation and Cancer: Respirable Particulate Matter, Fibrous Dusts and Ozone as Major Causes of Lung Carcinogenesis through Reactive Oxygen Species Mechanisms | |
Athanasios Valavanidis1  Thomais Vlachogianni2  Konstantinos Fiotakis2  | |
[1] Department of Chemistry, University of Athens, University Campus Zografou, Athens 15784, Greece; | |
关键词: reactive oxygen species; oxidative stress; inflammation; mechanisms of carcinogenesis; respirable particulate matter; ozone; tobacco smoke; | |
DOI : 10.3390/ijerph10093886 | |
来源: mdpi | |
【 摘 要 】
Reactive oxygen or nitrogen species (ROS, RNS) and oxidative stress in the respiratory system increase the production of mediators of pulmonary inflammation and initiate or promote mechanisms of carcinogenesis. The lungs are exposed daily to oxidants generated either endogenously or exogenously (air pollutants, cigarette smoke,
【 授权许可】
CC BY
© 2013 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202003190033721ZK.pdf | 298KB | download |