ARF1 and SAR1 GTPases in Endomembrane Trafficking in Plants

International Journal of Molecular Sciences

关键词: GTPases;    vesicular trafficking;    ARF1;    SAR1;    COPI;    COPII;   

DOI  :  10.3390/ijms140918181

来源: mdpi

【 摘 要 】

Small GTPases largely control membrane traffic, which is essential for the survival of all eukaryotes. Among the small GTP-binding proteins, ARF1 (ADP-ribosylation factor 1) and SAR1 (Secretion-Associated RAS super family 1) are commonly conserved among all eukaryotes with respect to both their functional and sequential characteristics. The ARF1 and SAR1 GTP-binding proteins are involved in the formation and budding of vesicles throughout plant endomembrane systems. ARF1 has been shown to play a critical role in COPI (Coat Protein Complex I)-mediated retrograde trafficking in eukaryotic systems, whereas SAR1 GTPases are involved in intracellular COPII-mediated protein trafficking from the ER to the Golgi apparatus. This review offers a summary of vesicular trafficking with an emphasis on the ARF1 and SAR1 expression patterns at early growth stages and in the de-etiolation process.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland