The Clinical Utilization of Circulating Cell Free DNA (CCFDNA) in Blood of Cancer Patients

International Journal of Molecular Sciences

Yahya I. Elshimali²  Husseina Khaddour¹  Marianna Sarkissyan²  Yanyuan Wu² 

[1] Laboratory Diagnostic Medicine, Faculty of Pharmacy, Mazzeh (17th April Street), Damascus University, Damascus, Syria; E-Mail:;Division of Cancer Research and Training, Department of Internal Medicine, Charles Drew University of Medicine and Science, 1720 East 120th Street, Los Angeles, CA 90059, USA; E-Mails:

关键词: circulating cell free DNA;    neoplasms;    early diagnosis;    follow up on cancer treatment;    prognosis;   

DOI  :  10.3390/ijms140918925

来源: mdpi

【 摘 要 】

Qualitative and quantitative testing of circulating cell free DNA (CCFDNA) can be applied for the management of malignant and benign neoplasms. Detecting circulating DNA in cancer patients may help develop a DNA profile for early stage diagnosis in malignancies. The technical issues of obtaining, using, and analyzing CCFDNA from blood will be discussed.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland