International Journal of Molecular Sciences | |
The Consequence of Oncomorphic |
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Pavla Brachova2  Kristina W. Thiel1  | |
[1] Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA; E-Mail:;Molecular and Cellular Biology Program, University of Iowa, Iowa City, IA 52242, USA; E-Mail: | |
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DOI : 10.3390/ijms140919257 | |
来源: mdpi | |
【 摘 要 】
Ovarian cancer is the most lethal gynecological malignancy, with an alarmingly poor prognosis attributed to late detection and chemoresistance. Initially, most tumors respond to chemotherapy but eventually relapse due to the development of drug resistance. Currently, there are no biological markers that can be used to predict patient response to chemotherapy. However, it is clear that mutations in the tumor suppressor gene
【 授权许可】
CC BY
© 2013 by the authors; licensee MDPI, Basel, Switzerland
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