Palladium-Catalyzed Intermolecular Oxidative Amination of Alkenes with Amines, Using Molecular Oxygen as Terminal Oxidant

Catalysts

Yasushi Obora¹ 

关键词: amination;    enamine;    allylic amine;    molybdovanadophosphate;    oxidative coupling;    alkenes;   

DOI  :  10.3390/catal3040794

来源: mdpi

【 摘 要 】

In this review, we summarize recent progress from our group with regard to Pd-catalyzed oxidative amination of alkenes with amines. Intermolecular oxidative amination of alkenes with secondary anilines was induced using a palladium-complex catalyst combined with molybdovanadophosphate as a co-catalyst under dioxygen, leading to allylic amines and enamines in good yields with high selectivities. The reaction proceeded efficiently, using molecular oxygen as the terminal oxidant. In addition, palladium-catalyzed oxidative amination of alkenes with anilines as primary amines was achieved using molecular oxygen as the sole oxidant, producing (Z)-N-alkenyl-substituted anilines in high yields.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.