Molecules | |
Synthesis of Bistetrahydroquinolines as Potential Anticholinesterasic Agents by Double Diels-Alder Reactions | |
Yorley Duarte1  Margarita Gutiérrez1  Luis Astudillo1  Jans Alzate-Morales2  | |
[1] Laboratorio Síntesis Orgánica, Instituto de Química de Recursos Naturales, Universidad de Talca, Casilla 747, Talca 3460000, Chile; E-Mails:;Centro de Bioinformática y Simulación Molecular, Universidad de Talca, 2 Norte 685, Casilla 721, Talca 3460000, Chile; E-Mails: | |
关键词: bistetrahydroquinolines; Diels-Alder reaction; AChE and BuChE inhibitors; molecular docking; MM-GBSA; | |
DOI : 10.3390/molecules181012951 | |
来源: mdpi | |
【 摘 要 】
The tetrahydroquinoline ring system is a unit found in many biologically active natural products and pharmacologically relevant therapeutic agents. A new series of bistetrahydroquinolines (
【 授权许可】
CC BY
© 2013 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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RO202003190032446ZK.pdf | 619KB | download |