The Henry Reaction in [Bmim][PF6]-based Microemulsions Promoted by Acylase

Molecules

Wen-Jian Xia²  Zong-Bo Xie¹  Guo-Fang Jiang² 

[1] School of Chemistry, Biology and Material Science, East China Institute of Technology, Nanchang 330013, China;

关键词: Henry reaction;    acylase;    water-in-[Bmim][PF₆] microemulsion;    enzyme promiscuity;   

DOI  :  10.3390/molecules181113910

来源: mdpi

【 摘 要 】

An environmentally-friendly, enzyme-promoted procedure for the Henry reaction was first studied using water-in-[Bmim][PF₆] microemulsions as reaction medium. The Amano acylase from Aspergillus oryzae showed better catalytic activity for the addition reactions of nitromethane with a series of aromatic aldehydes, and a highest yield of 90% was obtained.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.