New Constituents from the Korean Sponge Plakortis simplex

Marine Drugs

Jung Soon Oh²  Buyng Su Hwang²  Ok-Hwa Kang¹  Dong-Yeul Kwon¹ 

[1] College of Pharmacy and Wonkwang-Oriental Medicines Research Institute, Institute of Biotechnology, Wonkwang University, Jeonbuk 570-749, Korea; E-Mails:;Department of Oceanography, Kunsan National University, Jeonbuk 573-701, Korea; E-Mails:

关键词: Plakortis simplex;    cyclic peroxide;    cyclic peroxyketal;    pyridinium;    NMR;   

DOI  :  10.3390/md11114407

来源: mdpi

【 摘 要 】

Six new cyclic peroxides (1–6) were isolated from the Korean sponge Plakortis simplex, along with two new alkylpyridinium alkaloids (7 and 8). The structures of these compounds were completely determined by a combination of NMR analysis and chemical reactions. Compounds 1–6 exhibited cytotoxic/antifungal activities against RAW264.7 cells and Candida albicans.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.