Nutraceutical Value of Black Cherry Prunus serotina Ehrh. Fruits: Antioxidant and Antihypertensive Properties

Molecules

Francisco J. Luna-Vázquez⁴  César Ibarra-Alvarado¹  Alejandra Rojas-Molina¹  Juana I. Rojas-Molina¹  Elhadi M. Yahia²  Dulce M. Rivera-Pastrana²  Adriana Rojas-Molina³ 

[1] Laboratorio de Investigación Química y Farmacológica de Productos Naturales, Facultad de Química, Universidad Autónoma de Querétaro, Querétaro Qro.76010, Mexico; E-Mails:;Laboratorio de Fitoquímicos y Nutrición, Facultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Querétaro Qro.76230, Mexico; E-Mails:;División de Estudios de Posgrado, Facultad de Ingeniería, Universidad Autónoma de Querétaro, Querétaro Qro. 76010, Mexico; E-Mail:;Doctorado en Ciencias Biológicas y de la Salud, Universidad Autónoma Metropolitana, Unidad Xochimilco, México D.F. 04960, Mexico; E-Mail:

关键词: Prunus serotina;    black cherry;    polyphenols;    antioxidant capacity;    vasorelaxant effect;    antihypertensive effect;   

DOI  :  10.3390/molecules181214597

来源: mdpi

【 摘 要 】

In Mexico black cherry (Prunus serotina Ehrh.) fruits are consumed fresh, dried or prepared in jam. Considering the evidence that has linked intake of fruits and vegetables rich in polyphenols to cardiovascular risk reduction, the aim of this study was to characterize the phenolic profile of black cherry fruits and to determine their antioxidant, vasorelaxant and antihypertensive effects. The proximate composition and mineral contents of these fruits were also assessed. Black cherry fruits possess a high content of phenolic compounds and display a significant antioxidant capacity. High-performance liquid chromatography/mass spectrometric analysis indicated that hyperoside, anthocyanins and chlorogenic acid were the main phenolic compounds found in these fruits. The black cherry aqueous extract elicited a concentration-dependent relaxation of aortic rings and induced a significant reduction on systolic blood pressure in L-NAME induced hypertensive rats after four weeks of treatment. Proximate analysis showed that black cherry fruits have high sugar, protein, and potassium contents. The results derived from this study indicate that black cherry fruits contain phenolic compounds which elicit significant antioxidant and antihypertensive effects. These findings suggest that these fruits might be considered as functional foods useful for the prevention and treatment of cardiovascular diseases.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.