Multicomponent Click Synthesis of New 1,2,3-Triazole Derivatives of Pyrimidine Nucleobases: Promising Acidic Corrosion Inhibitors for Steel

Molecules

Rodrigo González-Olvera¹  Araceli Espinoza-Vázquez¹  Guillermo E. Negrón-Silva¹  Manuel E. Palomar-Pardavé²  Mario A. Romero-Romo² 

[1] Departamento de Ciencias Básicas, Universidad Autónoma Metropolitana, Av. San Pablo No. 180, México D.F., C.P. 02200, Mexico; E-Mails:;Departamento de Materiales, Universidad Autónoma Metropolitana, Av. San Pablo No. 180, México D.F., C.P. 02200, Mexico; E-Mails:

关键词: nucleobases;    multicomponent reaction;    1;    2;    3-triazoles;    acidic corrosion;    steel;   

DOI  :  10.3390/molecules181215064

来源: mdpi

【 摘 要 】

A series of new mono-1,2,3-triazole derivatives of pyrimidine nucleobases were synthesized by one-pot copper(I)-catalyzed 1,3-dipolar cycloaddition reactions between N-1-propargyluracil and thymine, sodium azide and several benzyl halides. The desired heterocyclic compounds were obtained in good yields and characterized by NMR, IR, and high resolution mass spectrometry. These compounds were investigated as corrosion inhibitors for steel in 1 M HCl solution, using electrochemical impedance spectroscopy (EIS) technique. The results indicate that these heterocyclic compounds are promising acidic corrosion inhibitors for steel.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.