Synthesis of Dimethyl Aryl Acylsulfonium Bromides from Aryl Methyl Ketones in a DMSO-HBr System

Molecules

Zhiling Cao²  Dahua Shi¹  Yingying Qu¹  Chuanzhou Tao¹  Weiwei Liu¹ 

[1] School of Chemical Engineering, Huaihai Institute of Technology, Lianyungang 222005, China;Jiangsu Key Laboratory of Marine Biotechnology, Jiangsu Institute of Marine Resources, Huaihai Institute of Technology, Lianyungang 222005, China

关键词: dimethyl aryl acylsulfonium;    aryl methyl ketones;    DMSO-HBr;    synthesis;    arylglyoxals;   

DOI  :  10.3390/molecules181215717

来源: mdpi

【 摘 要 】

A new, simplified method for the synthesis of dimethyl aryl acylsulfonium salts has been developed. A series of dimethyl aryl acylsulfonium bromides were prepared by the reaction of aryl methyl ketones with hydrobromic acid and dimethylsulfoxide (DMSO). This sulfonium salt confirms that bromine production and the bromination reaction take place in the DMSO-HBr oxidation system. What’s more, it is also a key intermediate for the synthesis of arylglyoxals.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.