Contemporary Network Proteomics and Its Requirements

Biology

Wilson Wen Bin Goh¹  Limsoon Wong¹ 

[1] School of Computing, National University of Singapore, 13 Computing Drive, Singapore 117417, Singapore; E-Mail:

关键词: proteomics;    networks;    systems biology;    bioinformatics;   

DOI  :  10.3390/biology3010022

来源: mdpi

【 摘 要 】

The integration of networks with genomics (network genomics) is a familiar field. Conventional network analysis takes advantage of the larger coverage and relative stability of gene expression measurements. Network proteomics on the other hand has to develop further on two critical factors: (1) expanded data coverage and consistency, and (2) suitable reference network libraries, and data mining from them. Concerning (1) we discuss several contemporary themes that can improve data quality, which in turn will boost the outcome of downstream network analysis. For (2), we focus on network analysis developments, specifically, the need for context-specific networks and essential considerations for localized network analysis.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.