Bioengineering | |
Mineralization and Characterization of Composite Lyophilized Gelatin Sponges Intended for Early Bone Regeneration | |
Isaac Rodriguez2  Gunjan Saxena1  Scott Sell3  | |
[1] Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Grosvenor Hall, Athens, OH 45701, USA; E-Mail:;Department of Biomedical Engineering, The University of Memphis and Joint University of Memphis-UTHSC-Memphis Biomedical Engineering Program, 119D Engineering Technology, Memphis, TN 38152, USA; E-Mail:;Department of Biomedical Engineering, Parks College of Engineering, Aviation, and Technology, Saint Louis University, 3507 Lindell Blvd., St. Louis, MO 63103, USA; E-Mail: | |
关键词: bone tissue engineering; platelet-rich plasma; hydroxyapatite; chitin; gelatin; simulated body fluid; bone graft substitute; | |
DOI : 10.3390/bioengineering1010062 | |
来源: mdpi | |
【 摘 要 】
The application of freeze-dried gelatin sponges as alternative bone grafting substitutes has many advantages, including the ability to swell, high porosity, tailorable degradation, and versatility to incorporate multiple components such as growth factors and nanofillers. The purpose of this study was to mineralize (M) and further characterize 1-Ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride (EDC) cross-linked gelatin sponges enhanced with preparations rich in growth factors, hydroxyapatite, and chitin whiskers (PHCE). Sponges were characterized for their swelling and
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190030095ZK.pdf | 1160KB | download |