Ultrasound-Assisted Extraction of Mangiferin from Mango (Mangifera indica L.) Leaves Using Response Surface Methodology

Molecules

Tang-Bin Zou²  En-Qin Xia²  Tai-Ping He²  Ming-Yuan Huang¹  Qing Jia² 

[1] Department of Sanitary Inspection, School of Public Health, Guangdong Medical College, Dongguan 523808, China; E-Mail:;Department of Nutrition and Food Hygiene, School of Public Health, Guangdong Medical College, Dongguan 523808, China; E-Mails:

关键词: ultrasonic-assisted extraction;    mangiferin;    mango leaves;    response surface methodology;   

DOI  :  10.3390/molecules19021411

来源: mdpi

【 摘 要 】

Mangiferin is a xanthone widely distributed in higher plants showing antioxidative, antiviral, anticancer, antidiabetic, immunomodulatory, hepatoprotective and analgesic effects. In the present study, an ultrasonic-assisted extraction method was developed for the effective extraction of mangiferin from mango leaves. Some parameters such as ethanol concentration, liquid-to-solid ratio, extraction temperature, and extraction time were optimized by single-factor experiment and response surface methodology. The optimal extraction conditions were 44% ethanol, the liquid-to-solid ratio was 38:1, and extraction for 19.2 min at 60 °C under ultrasound irradiation of 200 W. Under optimal conditions, the yield of mangiferin was 58.46 ± 1.27 mg/g. The results obtained are helpful for the full utilization of mango leaves, and also indicated that ultrasonic-assisted extraction is a very useful method for the extraction of mangiferin from plant materials.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.