Optimal Configuration for Relaxation Times Estimation in Complex Spin Echo Imaging

Sensors

Fabio Baselice¹  Giampaolo Ferraioli²  Alessandro Grassia¹ 

[1] Dipartimento di Ingegneria, Università degli Studi di Napoli Parthenope, Napoli 80143, Italy; E-Mails:;Dipartimento di Scienze e Tecnologie, Università degli Studi di Napoli Parthenope, Napoli 80143, Italy; E-Mail:

关键词: Magnetic Resonance Imaging;    complex decomposition;    statistical signal processing;    Cramer;    Rao lower bounds;    relaxation time estimation;   

DOI  :  10.3390/s140202182

来源: mdpi

【 摘 要 】

Many pathologies can be identified by evaluating differences raised in the physical parameters of involved tissues. In a Magnetic Resonance Imaging (MRI) framework, spin-lattice T₁ and spin-spin T₂ relaxation time parameters play a major role in such an identification. In this manuscript, a theoretical study related to the evaluation of the achievable performances in the estimation of relaxation times in MRI is proposed. After a discussion about the considered acquisition model, an analysis on the ideal imaging acquisition parameters in the case of spin echo sequences, i.e., echo and repetition times, is conducted. In particular, the aim of the manuscript consists in providing an empirical rule for optimal imaging parameter identification with respect to the tissues under investigation. Theoretical results are validated on different datasets in order to show the effectiveness of the presented study and of the proposed methodology.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.