Post-Polymerization Modifications of Polymeric Monolithic Columns: A Review

Chromatography

Sin Currivan¹ 

[1] Department of Analytical Chemistry, Faculty of Chemical Technology, University of Pardubice, Studentská 573, Pardubice 532 10, Czech Republic; E-Mail

关键词: polymer monoliths;    modifications;    HPLC;    CEC;    grafting;    click chemistry;    hypercross-linking;    nano-particles;   

DOI  :  10.3390/chromatography1010024

来源: mdpi

【 摘 要 】

The vast cache of methods used in polymeric monolithic column modification is presented herein, with specific attention to post-polymerization modification reactions. The modification of polymeric monolithic columns is defined and can include the modification of pre-existing surface groups, the addition of polymeric chains or indeed the addition of structures such as nano-particles and nano-structures. The use of these modifications can result in the specific patterning of monoliths, useful in microfluidic device design or in the investigation of modification optimization.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.