Molecules | |
Synthesis and Biological Evaluation of 2,4-Diaminopyrimidine-Based Antifolate Drugs against |
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Baskar Nammalwar1  N. Prasad Muddala1  Christina R. Bourne2  Mary Henry2  Philip C. Bourne2  Richard A. Bunce1  Esther W. Barrow2  K. Darrell Berlin1  | |
[1] Department of Chemistry, Oklahoma State University, 107 Physical Sciences, Stillwater, OK 74078, USA; E-Mails:;Department of Veterinary Pathobiology, Oklahoma State University, 250 McElroy Hall, Stillwater, OK 74078, USA; E-Mails: | |
关键词:
Gram-positive bacteria;
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DOI : 10.3390/molecules19033231 | |
来源: mdpi | |
【 摘 要 】
Due to the innate ability of bacteria to develop resistance to available antibiotics, there is a critical need to develop new agents to treat more resilient strains. As a continuation of our research in this area, we have synthesized a series of racemic 2,4-diaminopyrimidine-based drug candidates, and evaluated them against
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190028193ZK.pdf | 528KB | download |