Molecules | |
Celastrol Induces Apoptosis in Gefitinib-Resistant Non-Small Cell Lung Cancer Cells via Caspases-Dependent Pathways and Hsp90 Client Protein Degradation | |
Xing-Xing Fan1  Na Li1  Jian-Lin Wu1  Yan-Ling Zhou1  Jian-Xing He2  Liang Liu1  | |
[1] State Key Laboratory of Quality Research in Chinese Medicine, Macau Institute For Applied Research in Medicine and Health, Macau University of Science and Technology, Macau SAR, China;Guangzhou Institute of Respiratory Disease, State Key Laboratory of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China | |
关键词: celastrol; gefitinib resistance; NSCLC; apoptosis; Hsp90; EGFR; | |
DOI : 10.3390/molecules19033508 | |
来源: mdpi | |
【 摘 要 】
Celastrol, a triterpene extracted from the Chinese herb
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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