Selenium Fortification of an Italian Rice Cultivar via Foliar Fertilization with Sodium Selenate and Its Effects on Human Serum Selenium Levels and on Erythrocyte Glutathione Peroxidase Activity

Nutrients

Attilio Giacosa²  Milena Anna Faliva³  Simone Perna³  Claudio Minoia¹  Anna Ronchi¹ 

[1] Laboratorio di Misure Ambientali e Tossicologiche, Fondazione S. Maugeri, Istituto Scientifico di Pavia, Pavia 27100, Italy; E-Mails:;Department of Gastroenterology, Policlinico di Monza, Monza 20900, Italy; E-Mail:;Department of Applied Health Sciences, Azienda di Servizi alla Persona (ASP) di Pavia, University of Pavia, Pavia 27100, Italy; E-Mails:

关键词: food fortification;    erythrocyte glutathione peroxidise;    functional food;    rice;    trace element;    selenium;   

DOI  :  10.3390/nu6031251

来源: mdpi

【 摘 要 】

Selenium food fortification could be a cost-effective strategy to counteract the inadequacy of selenium intake among the Italian population. In this study, the effect of foliar fertilization with sodium selenate of an Italian rice cultivar and the increase of serum selenium and of erythrocyte glutathione peroxidase (GPx) activity after intake of fortified rice, have been evaluated. The effect of foliar fertilization with sodium selenate (50 g Se/ha) vs. water was studied. Moreover, in a randomized, double-blind study, 10 healthy women supplemented their usual diet with a daily dose of 80 g of Se-enriched-rice and 10 matched-women with 80 g of regular rice. Before, after 5 and 20 days of supplementation, serum Se and GPx-activity were evaluated. The mean selenium content in Se-enriched-rice was 1.64 ± 0.28 μg/g, while in regular rice it was 0.36 ± 0.15 μg/g (p < 0.001). A significant increase of serum Se and GPx-activity was observed only in the intervention group and only after 20 days. The results show that selenium fortification of rice can be achieved with foliar fertilization with sodium selenate and that the 20 days intake of this Se-enriched-rice increases the serum selenium levels and GPx-activity.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.