Goat Milk Fat Naturally Enriched with Conjugated Linoleic Acid Increased Lipoproteins and Reduced Triacylglycerol in Rats

Molecules

Raphaela Rodrigues⁴  Juliana Soares⁴  Hugo Garcia²  Claudenice Nascimento⁶  Maria Medeiros⁵  Marco Bomfim³  Maria Carmo Medeiros¹ 

[1] Departament of Nutrition, Universidade Federal de Pernambuco, Recife 50670-901, PE, Brazil;Departament of Morfology, Universidade Federal da Paraíba, João Pessoa 58051-900, PB, Brazil;Empresa Brasileira de Pesquisa Agropecuária, EMBRAPA Caprinos e Ovinos, Sobral 62010-970, CE, Brazil;Departament of Nutrition, Universidade Federal de Campina Grande, Cuité 58175-000, PB, Brazil;Departament of Physiology and Pathology, Universidade Federal da Paraíba, João Pessoa 58051-900, PB, Brazil;Escola Técnica de Saúde, Universidade Federal da Paraíba, João Pessoa 58051-900, PB, Brazil

关键词: lipids;    goat milk;    steatosis;    cholesterol;    lipoprotein;    rats;   

DOI  :  10.3390/molecules19033820

来源: mdpi

【 摘 要 】

Goat milk is source of different lipids, including conjugated linoleic acid (CLA). CLA reduces body fat and protect against cardiovascular diseases. In the present study fat from goat milk naturally enriched with CLA was used. Male Wistar rats were divided into three groups that received during a 10 week diet with different lipid sources: soybean oil (CON), coconut oil (CO) and goat milk fat naturally enriched with CLA (GM-CLA). We evaluated the effects of a GM-CLA on biochemistry parameters - high density lipoprotein (HDL), triacylglycerol (TAG), TAG/HDL ratio, total cholesterol and glucose -, body weight and histopathological aspects of the intestine and liver. GM-CLA increased body weight from the second to the fifth week of the experiment compared to CON. Feed intake differed between the CON group and GM-CLA early in the first to third week of the experiments and later between the ninth and tenth week. The CLA-diet group showed increased levels of HDL, reduced levels of TAG and TAG/HDL ratio and no effect on LDL, but enhanced total cholesterol. Serum glucose of the GM-CLA group showed no difference from the control group. Thus, a GM-CLA diet promoted growth in young rats and acted as protector of cardiovascular function, but further studies are still needed to clarify these effects.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.