Non-Conventional Methodologies in the Synthesis of 1-Indanones

Molecules

Manuela Oliverio¹  Monica Nardi³  Paola Costanzo¹  Luca Cariati¹  Giancarlo Cravotto⁴  Salvatore Vincenzo Giofrè² 

[1] Dipartimento di Scienze della Salute, Università Magna Graecia, Viale Europa, Germaneto (CZ) 88100, Italy; E-Mails:;Dipartimento Scienza del Farmaco e Prodotti per la salute, Università di Messina, Via Santissima Annunziata, Messina 98168, Italy, E-Mail:;Dipartimento di Chimica, Università della Calabria, Cubo 12C, Arcavacata di Rende (CS) 87036, Italy; E-Mail:;Dipartimento di Scienza e Tecnologia del Farmaco, Università di Torino, Via Pietro Giuria 9, Torino 10125, Italy; E-Mail:

关键词: 1-indanones;    microwaves;    ultrasound;    Q-tube™;    Friedel-Crafts acylation;   

DOI  :  10.3390/molecules19055599

来源: mdpi

【 摘 要 】

1-Indanones have been successfully prepared by means of three different non-conventional techniques, namely microwaves, high-intensity ultrasound and a Q-tube™ reactor. A library of differently substituted 1-indanones has been prepared via one-pot intramolecular Friedel-Crafts acylation and their efficiency and “greenness” have been compared.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.