Development of Drug Delivery Systems Based on Layered Hydroxides for Nanomedicine

International Journal of Molecular Sciences

Farahnaz Barahuie¹  Mohd Zobir Hussein¹  Sharida Fakurazi² 

[1] Materials Synthesis and Characterization Laboratory, Institute of Advanced Technology (ITMA), Universiti Putra Malaysia, UPM, Serdang 43400, Malaysia; E-Mails:;Laboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, UPM, Serdang 43400, Malaysia; E-Mail:

关键词: layered hydroxides;    nanomedicine;    drug delivery;    nanocomposite;    nanocarrier;    LDH;    ZLH;    cytotoxicity assay;   

DOI  :  10.3390/ijms15057750

来源: mdpi

【 摘 要 】

Layered hydroxides (LHs) have recently fascinated researchers due to their wide application in various fields. These inorganic nanoparticles, with excellent features as nanocarriers in drug delivery systems, have the potential to play an important role in healthcare. Owing to their outstanding ion-exchange capacity, many organic pharmaceutical drugs have been intercalated into the interlayer galleries of LHs and, consequently, novel nanodrugs or smart drugs may revolutionize in the treatment of diseases. Layered hydroxides, as green nanoreservoirs with sustained drug release and cell targeting properties hold great promise of improving health and prolonging life.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland