Dynamic Processes in Prochiral Solvating Agents (pro-CSAs) Studied by NMR Spectroscopy

Symmetry

Jan Labuta¹  Shinsuke Ishihara¹  Katsuhiko Ariga¹ 

[1] World Premier International (WPI) Research Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan; E-Mails:

关键词: prochiral solvating agent;    pro-CSA;    host–guest complexation;    charge transfer complex;    hydrogen bond;    enantiomeric excess;    chirality;    ¹H-NMR;    tetrapyrrole;   

DOI  :  10.3390/sym6020345

来源: mdpi

【 摘 要 】

Several dynamic processes, including tautomerism and macrocyclic inversion, in ¹H-NMR prochiral solvating agents (pro-CSAs) are investigated. Various features of pro-CSA, including modes of interaction for complex formation, stoichiometry, binding strength and temperature effects were compared for three representative pro-CSA molecules. Structural effects of conjugated tetrapyrrole pro-CSA on the mechanism of enantiomeric excess determination are also discussed. Detailed analysis of species (complexes) and dynamic processes occurring in solution and their ¹H-NMR spectral manifestations at various temperatures is presented.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.