A Simple Hydrophilic Palladium(II) Complex as a Highly Efficient Catalyst for Room Temperature Aerobic Suzuki Coupling Reactions in Aqueous Media

Molecules

Mengping Guo¹  Shiwen Liu¹  Xiuling Zhou¹  Meiyun Lv¹  Sanbao Chen¹ 

[1] Institue of Coordination Catalysis, College of Chemistry and Bio-Engineering, Yichun University, Yichun 336000, China; E-Mails:

关键词: hydrophilic catalyst;    aqueous media;    green chemistry;    Suzuki reaction;   

DOI  :  10.3390/molecules19056524

来源: mdpi

【 摘 要 】

A study on room temperature Suzuki cross-coupling in an aqueous medium was carried out using a simple hydrophilic palladium (II) complex, trans-PdCl₂(NH₂CH₂COOH)₂ as catalyst in the presence of K₂CO₃ in air. This approach with a comparatively inexpensive and hydrophilic catalyst, mild reaction condition and aqueous media exhibits excellent catalytic activity towards the Suzuki coupling of aryl bromides and arylboronic acids, and good yields were obtained in the Suzuki coupling of activated aryl chlorides.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.