Molecules | |
An Efficient Synthesis of Pyridoxal Oxime Derivatives under Microwave Irradiation | |
Dajana Gašo-Sokač1  Valentina Bušić1  Mario Cetina2  | |
[1] Josip Juraj Strossmayer University of Osijek, Faculty of Food Technology Osijek, Kuhačeva 20, 31000 Osijek, Croatia; E-Mail:;University of Zagreb, Faculty of Textile Technology, Department of Applied Chemistry, Prilaz baruna Filipovića 28a, 10000 Zagreb, Croatia | |
关键词: eco-friendly quaternization; microwave synthesis; phenacyl bromides; pyridoxal oxime; | |
DOI : 10.3390/molecules19067610 | |
来源: mdpi | |
【 摘 要 】
Quaternary salts of pyridoxal oxime have been synthesized by the quaternization of pyridoxal oxime with substituted phenacyl bromides using microwave heating. Microwave-assisted rapid synthesis was done both in solvent (acetone) and under solvent-free conditions. Good to excellent yields (58%–94%) were obtained in acetone in very short reaction times (3–5 min) as well as in the solvent-free procedure (42%–78%) in very short reaction times (7–10 min) too. Effective metodologies for the preparation of pyridoxal oxime quaternary salts, having the advantagies of being eco-friendly, easy to handle, and performed in shorter reactions time are presented. The structure of compound
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190025322ZK.pdf | 409KB | download |