Bis-naphtho-γ-pyrones from Fungi and Their Bioactivities

Molecules

Shiqiong Lu²  Jin Tian²  Weibo Sun²  Jiajia Meng²  Xiaohan Wang²  Xiaoxiang Fu²  Ali Wang²  Daowan Lai²  Yang Liu¹ 

[1] Institute of Agro-products Processing Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, China;MOA Key Laboratory of Plant Pathology, Department of Plant Pathology, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China; E-Mails:

关键词: bis-naphtho-γ-pyrones;    chaetochromin;    asperpyrone;    nigerone;    fungi;    biological activities;   

DOI  :  10.3390/molecules19067169

来源: mdpi

【 摘 要 】

Bis-naphtho-γ-pyrones are an important group of aromatic polyketides derived from fungi. They have a variety of biological activities including cytotoxic, antitumor, antimicrobial, tyrosine kinase and HIV-1 integrase inhibition properties, demonstrating their potential applications in medicine and agriculture. At least 59 bis-naphtho-γ-pyrones from fungi have been reported in the past few decades. This mini-review aims to briefly summarize their occurrence, biosynthesis, and structure, as well as their biological activities. Some considerations regarding to synthesis, production, and medicinal and agricultural applications of bis-naphtho-γ-pyrones are also discussed.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.