Quinone and Hydroquinone Metabolites from the Ascidians of the Genus Aplidium

Marine Drugs

Camila Spereta Bertanha¹  Ana Helena Januário¹  Tavane Aparecida Alvarenga¹  Letໜia Pereira Pimenta¹  Márcio Luis Andrade e Silva¹  Wilson Roberto Cunha¹ 

[1] Center for Research in Exact and Technological Sciences, University of Franca, Avenue Doutor Armando Salles Oliveira, 201, Franca, São Paulo 14404-600, Brazil;

关键词: ascidian secondary metabolites;    structure elucidation;    bioactivity;    ¹³C-NMR spectral data;    quinones;    hydroquinones;   

DOI  :  10.3390/md12063608

来源: mdpi

【 摘 要 】

Ascidians of the genus Aplidium are recognized as an important source of chemical diversity and bioactive natural products. Among the compounds produced by this genus are non-nitrogenous metabolites, mainly prenylated quinones and hydroquinones. This review discusses the isolation, structural elucidation, and biological activities of quinones, hydroquinones, rossinones, longithorones, longithorols, floresolides, scabellones, conicaquinones, aplidinones, thiaplidiaquinones, and conithiaquinones. A compilation of the ¹³C-NMR spectral data of these compounds is also presented.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.