Molecules | |
Evaluation of a Triple-Helical Peptide with Quenched Fluorophores for Optical Imaging of MMP-2 and MMP-9 Proteolytic Activity | |
Xuan Zhang1  Jamee Bresee1  Philip P. Cheney4  Baogang Xu3  Manishabrata Bhowmick2  Mare Cudic2  Gregg B. Fields2  | |
[1] Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15219, USA; E-Mails:;Torrey Pines Institute for Molecular Studies, 11350 SW Village Parkway, Port St. Lucie, FL 34987, USA; E-Mails:;Department of Radiology, Washington University in St Louis, St Louis, MO 63110, USA; E-Mail:;Department of Chemistry and Biochemistry, University of Denver, Denver, CO 80208, USA; E-Mail: | |
关键词: matrix metalloproteinase-2 (MMP-2); MMP-9; gelatinase; triple-helical peptides; optical imaging; fluorescence molecular tomography (FMT); | |
DOI : 10.3390/molecules19068571 | |
来源: mdpi | |
【 摘 要 】
Matrix metalloproteinases (MMP) 2 and 9, the gelatinases, have consistently been associated with tumor progression. The development of gelatinase-specific probes will be critical for identifying
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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RO202003190024780ZK.pdf | 2154KB | download |