Pregnancy Loss Following Amniocentesis or CVS Sampling—Time for a Reassessment of Risk

Journal of Clinical Medicine

Caroline Ogilvie¹ 

[1] Guy’s and St. Thomas’ NHS Foundation Trust and King’s College, London SE1 9RT, UK

关键词: miscarriage;    procedure-related pregnancy loss;    amniocentesis;    chorionic villus sampling (CVS);    non-invasive prenatal testing;    cell free fetal DNA;   

DOI  :  10.3390/jcm3030741

来源: mdpi

【 摘 要 】

Risk of procedure-related pregnancy loss is currently widely quoted in the UK as 1% for amniocentesis and 1.5% for chorionic villus sampling. Published data suggest that these risk figures are out of date and inaccurate, and that new guidelines are required for pre-test counseling. It is our opinion that accurate and evidence-based information concerning miscarriage risk is vital when counseling women, as exaggeration of this risk may deter women from testing, or cause unjustified remorse if a miscarriage ensues. It is also essential that health-care economists are aware of the up-to-date evidence on “procedure-related risk” when applying risk-benefit analysis to assess new technology for non-invasive screening.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.