Screening and Invasive Testing in Twins

Journal of Clinical Medicine

Giovanni Monni¹  Ambra Iuculano² 

[1] Department of Obstetrics and Gynecology, Prenatal and Preimplantation Genetic Diagnosis, Fetal Therapy, Ospedale Microcitemico, via Jenner, 09121 Cagliari, Italy;

关键词: twins;    screening;    invasive diagnosis;    therapy;   

DOI  :  10.3390/jcm3030865

来源: mdpi

【 摘 要 】

Prenatal screening and testing for trisomy 21 in twin pregnancies poses a number of challenges: the exact estimate of the a priori risk of trisomy 21, the choice of prenatal screening test and/or invasive techniques to employ for the diagnosis and the impact of the result on the options of treatment in case of discordant results within a twin pair or among multiples. These different aspects are discussed below while recognizing that many issues remain unresolved.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.