Simultaneous Electrochemical Detection of Dopamine and Ascorbic Acid Using an Iron Oxide/Reduced Graphene Oxide Modified Glassy Carbon Electrode

Sensors

Teo Peik-See¹  Alagarsamy Pandikumar¹  Huang Nay-Ming¹  Lim Hong-Ngee² 

[1] Low Dimensional Materials Research Centre, Department of Physics, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia; E-Mail:;Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, UPM Serdang, Selangor 43400, Malaysia; E-Mails:

关键词: graphene;    magnetite;    dopamine;    ascorbic acid;    biosensor;    electrochemical sensor;   

DOI  :  10.3390/s140815227

来源: mdpi

【 摘 要 】

The fabrication of an electrochemical sensor based on an iron oxide/graphene modified glassy carbon electrode (Fe₃O₄/rGO/GCE) and its simultaneous detection of dopamine (DA) and ascorbic acid (AA) is described here. The Fe₃O₄/rGO nanocomposite was synthesized via a simple, one step in-situ wet chemical method and characterized by different techniques. The presence of Fe₃O₄ nanoparticles on the surface of rGO sheets was confirmed by FESEM and TEM images. The electrochemical behavior of Fe₃O₄/rGO/GCE towards electrocatalytic oxidation of DA was investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) analysis. The electrochemical studies revealed that the Fe₃O₄/rGO/GCE dramatically increased the current response against the DA, due to the synergistic effect emerged between Fe₃O₄ and rGO. This implies that Fe₃O₄/rGO/GCE could exhibit excellent electrocatalytic activity and remarkable electron transfer kinetics towards the oxidation of DA. Moreover, the modified sensor electrode portrayed sensitivity and selectivity for simultaneous determination of AA and DA. The observed DPVs response linearly depends on AA and DA concentration in the range of 1–9 mM and 0.5–100 μM, with correlation coefficients of 0.995 and 0.996, respectively. The detection limit of (S/N = 3) was found to be 0.42 and 0.12 μM for AA and DA, respectively.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.